Products

Dexoprazol

Indication
Gastro-osephogeal Reflux Peptic Ulcer

Pharmaceutical Form
Dual Released Pillets

Dexlansoprazole 30mg
Like lansoprazole, dexlansoprazole permanently binds to the proton pump and blocks it, preventing the formation of gastric acid.

Dexlansoprazole ((R)-(+)-lansoprazole) has the same binding affinity to the proton pump as the (S)-enantiomer, but is associated with a three- to five-fold greater area under the plasma drug concentration time curve (AUC) compared with (S)-lansoprazole. With its dual release pharmaceutical formulation, the first quick release produces a plasma peak concentration about one hour after application, with a second retarded release producing another peak about four hours later. As of November 2009, clinical relevance of this form of release has yet to be shown.

History

Dexlansoprazole is used to heal and maintain healing of erosive esophagitis and to treat heartburn associated with gastroesophageal reflux disease (GERD).
 It lasts longer than lansoprazole, to which it is chemically related, and needs to be taken less often, making it possible to better control gastric acid.

Used once daily or as recommended by physician